Research Projects

FS I : Modelling methods for regenerative systems

Project coordination:

          Prof. Dr. rer. nat. habil. Andreas Heuer • Prof. Dr.-Ing. habil. Heidrun Schumann
          Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher • Prof. Dr.-Ing. Alke Martens

Subprojects
  • U_K_1 - Definition and Realization of a platform for the composition of simulation models
    (Oct 01 2006  until  Jun 01 2008)

  

Scientific coordination : Prof. Dr. rer. nat. habil.  Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Mathias Röhl

  • H3_1 - Distributed information retrieval using web based nets
    (Jan 01 2009  until  Nov 30 2011)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Andreas Heuer
Scientific staff :                Dipl.-Inf. Ron Henkel

  • Uhrm_A1 - Multi-level modeling of cell-biological systems
    (Oct 15 2009  until  Oct 14 2011)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Carsten Maus

  • M1 - e-Learning modeling and simulation for biologists
    (Mar 01 2009  until  Apr 01 2011)

  

Scientific coordination : Prof. Dr.-Ing. Alke Martens
Scientific staff :                Dipl.-Ing. Géraldine Ruddeck

  • U1 - Structure and space in modeling regenerative systems
    (Dec 01 2006  until  Aug 26 2010)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Mathias John

  • H1 - Defining and storing model components
    (Dec 01 2006  until  Nov 30 2010)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Andreas Heuer
Scientific staff :                Dr.-Ing. Dagmar Waltemath

  • S1 - Visual Support for the Development of Methods and Models for Regenerative Systems
    (Feb 01 2007  until  May 14 2010)

  

Scientific coordination : Prof. Dr.-Ing. habil. Heidrun Schumann
Scientific staff :                Dr.-Ing. Andrea Unger

  • S2 - Visual Data Mining of Complex Structure
    (Nov 01 2006  until Jun 09 2010)

  

Scientific coordination : Prof. Dr.-Ing.  habil. Heidrun Schumann
Scientific staff :                Dr.-Ing. Hans-Jörg Schulz

  • Mart_K1 - Game-based Learning
    (Feb 01 2010  until  Dec 01 2011)

  

Scientific coordination : Prof. Dr.-Ing. Alke Martens
Scientific staff :                Dipl.-Inf., Lic., M.A. Dennis Maciuszek

  • S_K_1 - Visual Data Mining visualization design for exploration of climate data
    (Oct 01 2006  until  Nov 01 2007)

  

Scientific coordination : Prof. Dr.-Ing. habil. Heidrun Schumann
Scientific staff :                Dr.-Ing. Thomas Nocke

  • Uhrm_A2 - Stochastic, Discrete Modelling of Cell Biological Processes in Continuous Space
    (Apr 15 2010  until  Mar 31 2012)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Arne Bittig

FS II : Simulation methods for regenerative systems

Project coordination:

          Prof. Dr.-Ing. habil. Heidrun Schumann • Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
          Prof. Dr. Olaf Wolkenhauer • Prof. Dr. rer. nat. Lars Schwabe • Prof. Dr. rer. nat. habil. Karsten Wolf

Subprojects
  • Uhrm_K0 - Automatic algorithm selection for complex simulation problems
    (Dec 01 2006  until  Oct 15 2010)

  

Scientific coordination : Prof. Dr. rer. nat. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Roland Ewald

  • Schu_A1 - Visual support for validation and verification of models
    (Feb 01 2010  until Jan 01 2012)

  

Scientific coordination : Prof. Dr.-Ing. habil. Heidrunn Schumann
Scientific staff :                Dipl.-Inf. Clemens Holzhüter

  • Schu_A2 - Multi-Level Visualization of Dynamic Complex Graphs
    (Jan 01 2010  until  Dec 31 2012)

  

Scientific coordination : Prof. Dr.-Ing. habil.  Heidrun Schumann
Scientific staff :                Dr.-Ing. Steffen Hadlak

  • Uhrm_K1 - Integration of workflows in modeling and simulation
    (Oct 01 2009  until  Apr 30 2011)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Stefan Rybacki

  • Uhrm_K2 - Experimental Model Validation
    (May 01 2008  until  Apr 01 2012)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Stefan Leye

  • Schu_K1 - Visual Analytics of heterogeneuos data
    (Sep 01 2009  until  Dec 01 2010)

  

Scientific coordination : Prof. Dr.-Ing. habil. Heidrun Schumann
Scientific staff :                Dr.-Ing. Marc Streit

  • U2 - Efficient and flexible simulators for cell biological systems
    (Feb 01 2007  until  Oct 19 2010)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Matthias Jeschke

  • Schw_A1 - Multi-scale modeling and simulation of neural systems
    (Jan 01 2010  until  Dec 31 2012)

  

Scientific coordination : Prof. Dr. rer. nat. Lars Schwabe
Scientific staff :                Dr.-Ing. Youwei Zheng

  • Uhrm_K3 - Brownian-Dynamics-Simulaton for cell biological applications
    (Aug 01 2009  until Sep 01 2012)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Fiete Haack

FS III : Biological systems and regenerative systems

Project coordination:

          Prof. Dr. med. habil. Arndt Rolfs • Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
          Prof. Dr. rer. nat. Dieter G. Weiss • Prof. Dr. Olaf Wolkenhauer

Subprojects
  • Weis_A1 - The reorganization of the cytoskeleton during Wnt-mediated neuronal differentiation
    (Oct 01 2009  until  Sep 01 2011)

  

Scientific coordination : Prof. Dr. rer. nat. Dieter G. Weiss
Scientific staff :                Dr. rer. nat. Heiko Lemcke

  • Wolk_A1 - A systems biology approach to dynamic modelling of signalling pathways and their characterization through quantitative measures
    (Feb 01 2010  until Jan 01 2011)

  

Scientific coordination : Prof. Dr. Olaf Wolkenhauer
Scientific staff :                Dr.-Ing. Simone Frey

  • Wolk_K1 - Mathematical modelling of cellular signal transduction: kinetic properties of the Wnt-signalling pathway
    (Feb 01 2010  until  Jan 01 2012)

  

Scientific coordination : Prof. Dr. Olaf Wolkenhauer
Scientific staff :                Dr. -Ing. Yvonne Schmitz

  • Rolf_K1 - in vitro and in silico exploration of the Wnt/β-catenin signaling pathway during differentiation oh human neural progenitor cells
    (Oct 01 2010  until  Sep 01 2012)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                Dr. -Ing. Orianne Mazemondet

  • W1 - Wnt Signalling mediated changes in the cytoskeleton motor enzyme system: Active and passive role in the differentiation of neural progenitor cells
    (Oct 01 2006  until  Sep 30 2009)

  

Scientific coordination : Prof. Dr. rer. nat. Dieter G. Weiss
Scientific staff :                Dr. rer. nat. Benjamin M. Bader

  • Wo1 - The influence of spatial aspects and feedbacks on the dynamics of intercellular signal transmission
    (Oct 01 2006  until  Sep 30 2009)

  

Scientific coordination : Prof. Dr. Olaf Wolkenhauer
Scientific staff :                Dr -Ing. Yvonne Schmitz

  • R2 - The Wnt dependent calcium signal path in the differentiation of human neural progenitor cells
    (Oct 01 2006  until  Sep 30 2009)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                Dr. rer. nat. Rayk Hübner

  • W2 - Interference of the canonical Wnt pathway and apoptosis signalling pathways during proliferation and differentiation of neural progenitor cells
    (Oct 01 2006  until  Sep 30 2009)

  

Scientific coordination : Prof. Dr. rer. nat. Dieter G. Weiss
                                           Dr. rer. nat. Ralf Kriehuber
Scientific staff :                Dr. rer. nat. Alexandra Jaeger

  • R1 - Analysis of the functional impact of the canonical Wnt Fz/Dsh/GSK-3β/β-catenin-signalling pathways for the differentiation of human neural progenitor cells
    (Oct 01 2006  until  Sep 30 2009)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                Dr.-Ing. Orianne Mazemondet

  • Rolf_A1 - Effects of Wnt/calcium-pathway on the differentiation of ReNcell VM cells
    (Mar 01 2010  until  Feb 01 2012)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                M.Sc. Ajay N. V. Talabattula

  • Weis_A2 - Spatio-temporal dynamics of transient protein-protein interaction on the level of receptor complexes and in the cytoplasm
    (Oct 01 2006  until  Jul 01 2011)

  

Scientific coordination : Prof. Dr. rer. nat. Dieter G. Weiss
Scientific staff :                M.Sc. Elke Carolin Calamia

  • Rolf_A2 - Effects of Wnt5a and Wnt7a on the differentiation of human neural progenitor cells
    (Mar 01 2010  until  Mar 01 2012)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                Dr. rer. nat.  Carolin Mußmann (geb. Mahler)

  • Rolf_K2 - Influence of novel indolymaleimides on canonical Wnt signalling in human neural progenitor cells
    (Oct 01 2006  until  Apr 01 2011)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
Scientific staff :                Dr. rer. nat. Anne-Caroline Scnmöle

FS IV : X-topics which link the other research projects

Project coordination:

          Prof. Dr. rer. nat. habil. Andreas Heuer • Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
          Prof. Dr. med. habil. Arndt Rolfs • Prof. Dr. rer. nat. Dieter G. Weiss

Subprojects
  • Post PhD project I: Developing Methods for Integrating Wet-Lab and Dry-Lab Experiments
    (Apr 01 2008  until  May 01 2010)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Jan Himmelspach

  • Post PhD project II: Development and exploration of methods for an improved data base in particular regarding spatio-temporal processes in real time measurement for modelling and simulation
    (Oct 01 2006  until Oct 01 2008)

  

Scientific coordination : Prof. Dr. med. habil. Arndt Rolfs
                                           Prof. Dr. rer. nat. Dieter G. Weiss
Scientific staff :                Dr. rer. nat. Jana Frahm

  • Post PhD project III: Study of cross-talk between canonical and non-canonical wnt signaling pathways
    (Jul 01 2009  until  Mar 31 2011)

  

Scientific coordination : Prof. Dr. rer. nat. Dieter G. Weiss
Scientific staff :                Dr. rer. nat. Tareck Rharass

  • Post PhD project IV: Formal Description and Visual Representation of heterogeneous Information Landscapes
    (Aug 01 2010  until  Jan 31 2011)

  

Scientific staff :                Dr.-Ing. Hans-Jörg Schulz

  • Post PhD project V: Experiment Design and Simulation Execution for Biologists
    (Nov 15 2010  until  Mar 31 2011)

  

Scientific coordination : Prof. Dr. rer. nat. habil. Adelinde M. Uhrmacher
Scientific staff :                Dr.-Ing. Roland Ewald