Together with our RISE intern from Canada, Jacob Smith, we have investigated how different simulation models of the canonical Wnt signaling pathway are linked to each other by looking into the provenance of these. We have identified crucial information to describe the provenance of 19 Wnt signaling studies. Jacob has implemented WebProv, which we have used to store, display, and query the provenance information of these studies.
Our paper “Relating simulation studies by provenance—Developing a family of Wnt signaling models”, authored by Kai Budde, Jacob Smith, Pia Wilsdorf, Fiete Haack, and Adelinde M. Uhrmacher, will be published in the open-access journal PLOS Computational Biology. It will shortly be made available at https://doi.org/10.1371/journal.pcbi.1009227.